Manchester Terriers, both the Toy and Standard variety, have a sighthound ancestor (greyhound or whippet), and thus should be treated like them in terms of anesthetic regimes. They are lean, muscular dogs with low body fat, and metabolize anesthetic agents more slowly like sighthounds. 

Manchester Terriers tolerate premedication well prior to anesthesia with acepromazine/opioid combinations given IM or SQ, provided that acepromazine is used at the lowest effective dose. Barbiturates used for induction are metabolized slowly and will prolong recovery time; however small dosages of IV Thiopental used to effect are safe and do not result in excessive recovery time. Ketamine/diazepam IV or propofol IV following premedication are also effective induction agents. Anesthesia should always be maintained with an inhalant gas such as Sevoflurane or Isoflurane, as additional doses of induction agents will unnecessarily prolong recovery.  Read More...